• Generate the index file by tabix

    bgzip -c PrDSM_Grch37_20190304.vcf > PrDSM_Grch37_20190304.vcf.gz
    tabix -p vcf PrDSM_Grch37_20190304.vcf.gz

  • Genome Build

    PrDSM predictions used the GRCh37/hg19 genome build.

  • Running the Software

    Minimum requirements of usage:
    Tabix-0.2.6
    Add tabix to your PATH:
    export PATH=./tabix-0.2.6/:$PATH
    Download our pre-computed data:
    PrDSM_Grch37_20190304.vcf.gz
    PrDSM_Grch37_20190304.vcf.gz.tbi
    MD5Sums
    Benign mutations of the full independent dataset

    Usage:
    A synonymous variant, like this:
    tabix PrDSM_Grch37_20190304.vcf.gz chrom:start-end
    eg.
    tabix PrDSM_Grch37_20190304.vcf.gz 1:69096-69096 (tab-separated )
    Large batches of synonymous variants, like this:
    bash file_in.sh > file_out.vcf
    eg.
    #! /bin/sh
    tabix PrDSM_Grch37_20190304.vcf.gz 1:69096-69096
    tabix PrDSM_Grch37_20190304.vcf.gz 1:69099-69099
    tabix PrDSM_Grch37_20190304.vcf.gz 1:69102-69102